I took her back to the vet in November as I was so concerned about the weight gain. So, your vet will first determine what is causing the problem and treat the underlying issue. Wow so glad there are others who experienced hell with this drug. He has intermittent hotspots and a rash. Hes on IV fluids but not expected to live more than a week. The most common application of hydroxyzine for dogs is in relation to the treatment of pruritus. In some cases, more serious side effects may occur, such as infections or tumors. This made a huge difference for surgeries. All of the sudden it clicked. Try the new diet for 4 weeks. The Prozac after three weeks did nothing, his shaking and breathing became worse. They destroyed his stomach, his stomach was trembling, he lost appetite on and off, the last day when he collapsed was because he was not able to breathe due to a mass near his heart coming from the spleen had formed from taking this SHIT. If not Im going back to the vets. Knowing the medication was the only new thing in his routine, we stopped it. He is so sick he cant pick his head up. Good. You may even want to read about the legal definition of slander: http://definitions.uslegal.com/s/slander/. Due to her age, shes not the best at going outside, but on this pill, she is peeing constantly. Ive not noticed any of the side effects as of yet but after reading the comments, I will ask for blood work. Please let me know what I can do to help get this drug off the market. animals own cells. Carprofen is a non-steroidal anti-inflammatory drug (NSAID) that is used by veterinarians as a supportive treatment for the relief of arthritic symptoms in geriatric dogs. Research has found an ingredient known as praline-rich polypeptide (PRP) in bovine colostrum; it appears to be what is helping decrease the allergy symptoms. I now blame myself because I should have researched this medication before I gave it to her. His nose is cold and his behavior is normal, but we are very worried. She nearly died and has never been the same since. Probably more concerned with the monthly sale of Apoquel to me rather than reporting this AE. I should have ask questions I usually do. What kind of a vet would put a dog on a drug that My dog has no appetite and as of today, his nose had blood coming out of it. But then, she became actually fearful of people she formerly would jump up and down to give them kisses. Im not anti vet, I just think everyone needs to do their own research. After two trips to the vet, then being referred to a specialists, we learned his liver enzymes were off the charts. We rescued our Min Pin Buddy 8 yrs ago. I believe it is the medication that has caused them. After reading almost all of the comments on here I would think you would all exchange info and file a Class Action Lawsuit against the makers of this drug, the FDA for negligence, at least. i have a newfie who was poisoned by our landlord with outdated illegal weedkiller- at 8mos we almost lost her since that episoed she had become a chronic alergic dog, and not to fleas -environmental stuff -mildew,mold,pine needles .etc. Such as, what is the correct hydroxyzine dosage for dogs? The combination of the two can make a dog very sleepy. Apparently either your company representative, the veterinarians or both are not being made aware that this serious adverse event is occurring in dogs exposed to Apoquel with long term use. Apoquel can be used long-term at maintenance doses or seasonally as needed. It dawned on me to research apoquel. Recently we moved to a different side of town in a metropolitan area and needed to find a new vet. DrugBank Accession Number. How long has this been a concern? Beware aspergillosis infections due to Apoquel Everyone! Other veterinarians may have their short comings, but at least they are more concerned about their patients and less about their wallets. I have also found that by wiping his feet with a damp towel after he comes in from outside, there is far less itching and scratching. (Source: Cosgrove SB, Wren JA, Cleaver DM, et al. We had to use the Apoquel because he needed surgery for a torn ACL and couldnt use prednisone. In that years time though, she is constantly asking for food, drinks excessively, when she lays down to sleep her breathing sounds like she has an obstruction in her airway. keep me up all night and day biting,scratiching licking she is a happy dog. August 18, 2020 By //byThe Dogsnet Team 2 Comments. About three days into this drug she started acting very lethargic barely getting out of her bed. Great! Thank you all for comments. Here are my 7 most important natural remedies you should be considering: But she is now peeing like crazy and today in the house, first time EVER. This medication is not worth your puppys life. Nothing worked. About two weeks ago I went to bed on the Friday night and he was fine. I hope we stopped this drug in time before more serious damage happens. It has a different mechanism of action than steroids, cyclosporine, antihistamines, allergy shots and sublingual immunotherapy. When my vet called to tell me the results of all of the tests, everything was negative, I told her I was taking him off of APOQUEL. I was NOT told it suppresses the immune system, but it absolutely does. Never again will I use that drug. I have a 3year old german shepherd, itching like crazy Apoquel helps it keeps the itching undercontrol however he want to be outside all the time to pee, which is fine. I thought it might be his food, or too many treats, and last night I finally figured out it was the apoquell. She went on this medication because she got extremely itchy from going into the lake. These drugs were first discovered in the 1930s. As soon as spring arrived, the scratching and paw licking began. It helped a little but not enough, so a week later (yesterday) I called the vet, they prescribed Apoquel 5.4mg once every 12 hours for 14 days then once every 24 hours for 14 days. I usually research medications on the internet before taking them and this is the TRAGEDY OF MY LIFE, as I did not do it thoroughly, I trusted the doctor and when I looked it up I only read one first ad that pops up , ad from Zoetis, they only list vomiting, diarrhea and gastrointestinal problems, that right there should have been a Red flag for me, but again, THIS IS THE TRAGEDY OF MY LIFE. Has been on short term antibiotics and steroids for secondary skin infections. I have to give her water from a bottle or syringe. Key Points on Apoquel Unlike steroids, Apoquel side effects are minimal: no excessive thirst or hunger, no exces-sive urination, and no long-term negative effects on the liver Apoquel can cause rare intermittent GI symptoms For a 45-lb. And now me and my family have the heartache of thinking we was helping his allergy problem whenever this drug was killing him on the inside, please dont use this drug, no one wants there fur baby to die over a wrong decision a vet makes. I just think until you have an allergic dog, you are unaware how wide spread of a problem it is. However, his alk phos was literally off the chart and we could not get it down. Dr. Dwight Andrew Alleyne warns that "Allergies in dogs can be a unique experience for each pet. Just seems like a lot to me. However, we always recommend that you speak to your vet before starting any new medication, just to be sure. My 11 year old shih tzu has really terrible allergies once we moved from a large city to the suburbs he went downhill with allergies, it literally only took 4 hours before he started oozing green from his eyes. No more. No scratching, because she was too outta it to scratch. The dog lost 10 pounds and recovered from the UTI but the previous cancer returned and she become seriously ill very quickly and we lost our beautiful dog. My dog was prescribed this to help stop the itch for her mysterious skin infection / bacteria ( that the vet could not tell what it was after paying over $500.00). The next 24 hours passed and I saw his behavior change, He finally went to his water bowl, then asked to go out and potty. In addition to Allergies Atopy, and We were told to take her home and scheduled a full body scan by a professional x-ray tech. !!! He never does that, he always tells me when he has to go out. We stopped Apoquel today because Alk phos is very high on last two tests. There are also no drug Apoquel alternatives for dogs that are effective and safe. I took him to the vets this time because I got lazy. I hadnt associated the bed wetting with the Apoquel but based on others statements I think their is a connection. This weekend, she developed diarrhea. I think he had an overgrowth of yeast, so in february I tried nzymes.com. And dont forget if youre at all concerned about your pets medication, then give your veterinarian a quick ring. Read about the JAK inhibitors that protect your dog from developing immune diseases, these inhibitors PROTECT your dog, this drug turns them off. It is just like our medication do you honestly think the side effects are listed for us ? But just a few days later she was falling and pacing and panting. I was angry I was never told this when she gave me the med. Fuck this drug. I saw another yorkies mom on here post the almost identical thing as my girl is. 1.Less Allergenic Food. Drugs.com is where I found all the horrible side effects of the drug and it was too late. I have many questions, and was wondering does anyone who has had similar issues with apoquel know how long this nightmare of a drug stays in a dogs system. She almost immediately stopped itching and I was delighted. Since it is a short-acting drug, the effects will be gone in 24 hours; however, the medication may last longer in dogs with renal or liver impairment. Dogs under one year of age should not take Apoquel. My dog is a 2 and 1/2 year old yorkies. No more seizures so do yourself a favor and stay very far away from this medication. He is lethargic and seems to have aged rapidly. If these sort of dermatologic/parasitic overgrowths occurred in humans from treatment with JK inhibitors, it would certainly prompt the FDA to take action to protect the patient population utilizing these medications from these severe adverse events I am not a vet, just an educated pet owner who totally gets how frustrating it is to have an itchy dog. one-sixth the normal dose (1/2 tablet a day), he was unable to walk at all, and he developed increased thirst and increased urination The bonding after reviving her is incredibly tight. Along with this, came the increased urination. After tapering off the prednisone as prescribed, she was off to the races again. so I went back to my regular vet I trusted who pit Ollie on ever increasing steroids to try to kill this yeast infection. It stopped the itching immediately and he was finally able to get relief. I have two dogs, one that develops severe itching and skin yeast infection issues and the other severe ear yeast infections. I am so grateful to have finally found something that works and is healthy for her. Brand names: Chlor-Trimeton, Niramine, Iramine, Antihistalone. His skin is scaley and flakes like crazy. Active and happy. One leg even appears lumpy. He seemed confused and his coordination was way off. As always, if you have any further questions or concerns, please do not hesitate to contact us. She keeps getting infections in her anal gland area. Im at the end of the road here in my hopes for Ollie to be healthy. No drug is totally safe. 7.The last increasingly used ingredient for allergies is colostrum. My 6 year old french bull dog was put on Apoquel on 17/3/17 he had his first seizure on 2/4/17 he passed away on 4/4/17 my dog was fit and healthy up till his first seizure. Any advice????? Unfortunately the itching has started back up. She has been coned for about 2 years so when my Vet told me about Apoquel and how successful it has been I couldnt wait to try it. It stops the bone marrow from manufacturing red blood cells and your pet will get very ill, which may not be able to turn around. Her stools are turning around and while still soft, are not the plop plop plop anymore. My 15l.b Westie has been on Apoquel 3.6mg, twice daily since Jan.2016. Hydroxyzine HCl for dogs (brand names: Atarax or Vistaril) is an antihistamine indicated for allergy treatment in dogs and cats. The rate of adverse events overall was low (<5%) and included Just wish I could find it cheaper but she is well worth the $93/month I spend on her! I hate to consider long term effects of this drug. Side effects have been rarely seen and documented, but the most common occurrences have been mild vomiting and diarrhea. Hell no, healthy dogs mean less business. Yes, it stopped his itching but at what price? This dog was perfectly healthy and suddenly went down hill. I ran to the vet and asked for more$55 later, I had another months supply. He takes 16 mg. daily and the scratching has almost stopped. Hi. She is much more alert and somewhat less itchy. 5 days later & I still have a very very different dog He went from an extremely confident, friendly & vocal dog who was running round & playing all the time with my other dog into & nervous wreck & he also seems to still have discomfort in his bad leg. One morning I got up and he was shaking in his cage and couldnt lift his head. development of generalized demodicosis (after day 28). http://www.fda.gov/AnimalVeterinary/SafetyHealth/ProductSafetyInformation/ucm055369.htm. I have used Benadryl for big flare ups of his skin, dosing him at .5mg per lb ( I give 50lb Jessie 25mg of Benadryl at night), and Ill do it twice a day if needed. Despite providing the vet center with a copy of my letter to Zoetis and their request to have the vet contact them to discuss this AE, as of 9-6-19 the vet has not contacted them. One of the most common questions we get asked at the Apoquel blog is whether its safe to give our dogs antihistamines alongside their Apoquel medication. Ive had my terrier mix dog on Apoquel for a year and a half. Anytime a drug is taken side effects are possible. Antihistamines work by blocking the action of histamines. After 2 evenings, we suspected accumulative effects of pill and stopped it. He is a different dog entirely now that his life isnt consumed by itchiness and chewing and scratching. For the past month or so he just wasnt right; lethargic, increased ear infections and two weeks ago while chasing a ball it looked as though a linebacker took the legs out from under him, but only on his right side. See what it can do for your dog here: http://www.thedogsupplement.com. We even had a needle biopsy done. Other than some itching she has always been healthy. Liver counts are high is some areas so we will check again in two months. I think a class action suit against the makers of apparel is called for. There should be some mornings to the vets, but there arent. And Grandpuppy has a history of urinary tract issues, but after starting Apoquel her urinary tract problems are blamed on it by her owner. I wish I had researched this forum before. I started looking at this site or blog for answers for the insane paw licking my baby goes through every year around Aug., Sept. We thought we were going to lose her. I have also noted some days he does not want to eat. I took her off Apoquel a few days ago.. And had blood work done.. eye check revealed an ulcer on one eye, and she had Valley Fever test All came back negative, with the exception of high thyroid, but not high enough for alarm! We have a rescue dog, 3 yrs old now. The first month he took the full dose of 5.4, the second month we halved it. She was also drinking more and having accidents. acute, short-term condition or can be recurrent or chronicall which can impact the This year her suffering became unbearable. Between your irresponsible claims and your ridiculous supplement, you are a disgrace to the profession.. I tried to have the 10 pills she takes daily compounded by a vet pharmacy in Scottsdale, but the fillers they used caused her to start seizing, so now we just do the 10 pills a day of 1 med. I thought I had found relief for him and for us but obviously not. For us, Apoquel is a bad drug. I guess I need to do some more research. I certainly want her to be happy but also healthy. By example, many that are on chemo come to us for high dose IV vitamin C (50g-150g/infusion) Denise. the only side effects i have noticed is she is happy again. I have noticed she is urinating longer outside and now has gone potty in her crate on her bedding while we are at work, once on my area rug and then right in front of my husband on the bath mat. I know that an itching dog suffers, but I will try whatever I can to give her to be comfortable, and I know between the prednisone and apoquel she is probably being killed from the inside and I cannot do that to her. However, he also developed skin growths right around that time and they will not go away. Well I got home and gave her, her first dose not much longer after that she seemed higher than a kite, a few hours later she started throwing up clear foaming liquid (about 6 times in total from afternoon through out the night) she hasnt eaten anything, she licks at her lips quite a bit until she settles and has body shakes. Some of the horror stories above are frightening. His breathing labored at times and a runny nose. This morning I gave to him for a second time. I am going to take him back m to the vet but I think I will try antihistamines and other supplements. I am seriously thinking this drug is to blame. Keep in mind she has been on the Apoquel since the spring of 2014 when it came out. What is the lesser of the two evils? He still licks his paws a lot at night is the only symptom left. My dog died this past Sunday and had all of the Symtoms I have seen in most of this comments, he was clumsy and peed in weird places out of nowhere I knew what my dog ate and how heathy he was until this drug was giving to him. I am looking for suggestions on what to do. After 3 pills he started having seizures. NO. Do not use in breeding, pregnant, or nursing dogs. The Vet eventually suggested Apoquel. nothing major yet -except she doesnt 1.7m dogs were tested. I even had to duct tape socks to his feet. And the drug company should be ashamed of there self. However, when the pollen count starts to rise, so does the risk of our dogs suffering from allergies. Benadryl wasnt working so Dr. prescribed Apoquel 6/9/2016. I wouldnt take our dogs almost considered human to a vet i didnt trust. I am wondering who your employer is, Ms Moore, and what prompted you to comment? She is on Natural Balance fish and sweet potato formula and same brand of treats as she is allergic to wheat, gluten, chicken and beef. Nadya. Then he began acting weird one day starting with having diarrhea then he started panting, drooling, pacing, sitting on my chest I knew something was wrong and went to the animal emergency room. Any other prescription or over-the-counter medicines, herbal remedies, nutritional supplements, or vitamins. The et did not tell be the possible side effects. Gave this med to my 9 year old Rat Terrier.. now she is dead. Dogs treated with Apoquel works within four hours, controls allergy itching within 24 hours, and is safe for short-term and long-term usage. I wasnt told about these side affects nor given a handout. Apoquel is very dangerous. In a study, dogs were treated with Apoquel for more than 2 years. He is still dealing with the side effects of this medication. Diagnosis is a mite type(Demoditic? So, if your dog is pregnant it would be wise to discuss this with your vet. 3.Regular bathing- of your dogs feet as he comes in from outside, and of your entire dog. ..for a few weeks. Her body was like a noodle. I went to a different vet than prescribed the Apoquel and he reported having seen this in other dogs in response to Apoquel. I am convinced that apoquel is the cause and I would like to know if his liver enzymes will return to normal now that apoquel has been stopped. 2 days offnoticeable improvement. I decided to look up the side effects of Apoquel, as that was the only thing that was new and I wondered if GI upset and diarrhea could become an issue while on it. Auggie needs this medicine this medicine needs to be cheaper and safer for his liver and kidneys. Sooooo happy with it but All of a sudden, she has developed a whole new set of even more significant and really scary issues: She started going kiki accidentally, when she would start digging on furniture, in bed, where ever! The vet put him on Apoquel 16mg a day. Tried everything else. Strange about aggression as a side effect could it be she just doesnt feel good on the drug and irritable? Zoetis, Apoquel's manufacturer, conducted a long-term (two year) study examining 247 dogs and the side effects of Apoquel they experienced. I knew nothing about Apoquels side effects until I saw their commercial a couple of months ago where it states a lot of bad things that can happen to your pet including making cancer grow MUCH faster. However, I decided not to renew the script and I am currently looking for a cure for the problem, not a way to mask the symptoms with dangerous chemicals. Histamines are compounds in the body which are responsible for the symptoms we experience when we are allergic to something. Im going to take her off it and see if she calms down and gets back to her normal self. He seemed afraid to move, as if it caused him pain. She has been on 3 primary seizure drugs used in humans for almost a year now. There are 384 drugs known to interact with zonisamide, along with 11 disease interactions, and 1 alcohol/food interaction. Your email address will not be published. We went through a round of antibiotics (no help)and then an antifungal, which seemed to help. She slept on my bed and had since she was 10 weeks. Chlorpheniramine is an antihistamine, used to treat allergic skin disease in dogs . He is nibbling them constantly. She cant even find her toys unless I put them in her mouth. I contacted the makers of this pill. After reading all the comments, I have decided not to take the risk of harming my dog more by this drug. On February 15, 2018, Aries was back at the center with same issue and again a Rx issued for 70 Apoquel 5.4mg tabs with a charge of $138.60. Its been 2yrs of no Atopica. God knows how he pulled through but after 5 days he was on a turn in the right direction. We all need to do our part to get this drug off the market. This new vet prescribed Aproquel 16mg (twice daily 14 day supply) for a chronic allergy problem, we think from the cat. It was gradual, but now after seven days off the Apoquel, he is back to his normal self. Seonaid, what dose are you giving your westie? Apoquel is an allergy medication while Benadryl is an antihistamine. start with the lowest possible dose and increase gradually if needed. A blinded, randomized, placebo-controlled trial of the efficacy and safety of the Janus kinase inhibitor oclacitinib (Apoquel) in client-owned dogs with atopic dermatitis. This is because your vet will be able to advise you on the best course of action for your dog based on their individual health and medical history. Check with your vet before giving your dog any over-the-counter medication, even if it is safe for dogs. Cetirizine Hydrochloride for Dogs. I previously had him on Merrick Limited Ingredient Turkey which helped the diarrhea. Last few days have cut dose in half and itching is still under control. After 1 month she was reduced to 1 in the morning. Hope FDA takes this seriously as theres always the money making issue versus quality/safety now days. Were here at the next morning and she seems a tiny bit more alert. No visible side effects, her energy level is still high and her need to scratch that one spot on her back is barely noticeable. If there is anyone else out there with dogs on Apoquel as long as mine suffering from cancer I would like to know. She went into Cardiac Arrest and flat lined. After ten years of fighting severe inside of the paws allergies, to the point that this 150# dog could barely walk, I was elated that something finally worked. I have an eight year old cockapoo, who has been like my third child. However, it is not recommended that you do so. We will continue with weekly medicated baths and if necessary will increase frequency of these. I also wonder if advantix 2 would be responsible for his rash. The rest of your rant is not deserving of a reply: I chose to resign based on my personal beliefs, and I have enough guts to actually be public about it, including using my real name. Mornings to the vet in November as i was so concerned about your pets medication, then referred! Bed on the drug company should be some mornings to the profession scratching, because she was 10.... 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Bottle or syringe grateful to have finally found something that works and is safe for and! Came out before giving your Westie live more than a week stools are can my dog take apoquel and hydroxyzine together around and while still soft are.
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